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Microwave-mediated coupling of electron spins separated by more than 4 mm is demonstrated, suggesting the possibility of using photons at microwave frequencies to create long-range two-qubit gates between distant spins.
DNA replication in eukaryotes requires the histone variant H2A.Z, which binds the enzyme SUV420H1 to promote the dimethylation of histone H4, in turn recruiting the origin-recognition complex to activate early replication origins.
In mouse studies, metformin treatment results in increased secretion of growth/differentiation factor 15 (GDF15), which prevents weight gain in response to high-fat diet, and GDF15-independent lowering of circulating blood glucose.
Male and female B cells show differing abilities to localize and contribute to germinal centres, in a way that depends on the G-protein-coupled guidance receptor GPR174 and its chemokine ligand CCL21.
The leg-enriched sensory appendage protein, SAP2, confers pyrethroid resistance to Anopheles gambiae, through high-affinity binding of pyrethroid insecticides; an observed selective sweep in field mosquitoes mirrors the increasing resistance reported in Africa.
Both dietary and microbial factors influence the composition of the gut bile acid pool, which in turn modulates the frequencies and functionalities of RORγ-expressing colonic FOXP3+ regulatory T cells, contributing to protection from inflammatory colitis.
Analyses of the proportions of individuals who have completed key levels of schooling across all low- and middle-income countries from 2000 to 2017 reveal inequalities across countries as well as within populations.
The complex patterns of activity in motor cortex that control movements such as reach and grasp are dependent on both upstream neuronal activity in the thalamus and the current state of the cortex.
The cryo-EM structure of the γ-tubulin ring complex (γ-TuRC) from Xenopus laevis provides insights into the molecular organization of the complex, and shows that actin is a structural component that is functionally relevant to microtubule nucleation.
Theoretical modelling shows that elastic fluctuations can enable the tuning of metal-to-insulator transitions, potentially also explaining the dependence of the transition temperature on cation radius in perovskite transition-metal oxides.
A superposition of tunable photonic lattices is used to create optical moiré patterns and demonstrate the resulting localization of light waves through a mechanism based on flat-band physics.
Cryo-electron microscopy structures of the TniQ–Cascade complex encoded by the Vibrio cholerae Tn6677 transposon reveal the mechanistic basis of the functional association of CRISPR- and transposon-associated machineries.
The histone-acetylation-reader protein ENL is mutated in a paediatric kidney cancer in such a way that it clusters at target genes, increasing the recruitment of the transcriptional machinery, enhancing transcription and deregulating cell fate during development.
The potential for infinite persistence of planktonic predator and prey cycles is experimentally demonstrated and these cycles show resilience in the presence of stochastic events.
In theory, the anomalous quantum Hall effect is observed in edge channels of topological insulators when there is a magnetic energy gap at the Dirac point; this gap has now been observed by low-temperature photoelectron spectroscopy in Mn-doped Bi2Te3.
The genome of the tropical blue-petal water lily Nymphaea colorata and the transcriptomes from 19 other Nymphaeales species provide insights into the early evolution of angiosperms.
An intrinsic antiferromagnetic topological insulator, MnBi2Te4, is theoretically predicted and then realized experimentally, with implications for the study of exotic quantum phenomena.