Nature Reviews Genetics
Volume 9, No 12 December 2008
Featured Article
Epigenetic regulation of centromeric chromatin: old dogs, new tricks?
Robin C. Allshire & Gary H. Karpen
2007 ISI Impact Factor 22.399(*Source of Impact Factor data)
Poster and podcast
Next–generation sequencing technologies
Nature Genetics and Nature Reviews Genetics present a poster and podcast that explore the conceptual basis of next–generation sequencing technologies, their myriad applications and the challenges for the future. Access to both is free, thanks to support from Applied Biosystems.
CURRENT ISSUE
Review
Turning a hobby into a job: How duplicated genes find new functions
Gavin C. Conant & Kenneth H. Wolfe
Recent studies have advanced our understanding of gene classes that tend to undergo duplication, and how natural selection acts on them. The co–option of pre–existing, secondary protein functions is emerging as a widespread feature in the evolution of genetic novelty through gene duplication.
CURRENT ISSUE
Review
The evolution of animal chemosensory receptor gene repertoires: roles of chance and necessity
Masatoshi Nei, Yoshihito Niimura & Masafumi Nozawa
Recent studies have shown that there is enormous variation in the number of chemosensory receptor genes among the genomes of different organisms. Much of the variation can be explained by adaptation, but random duplication and deletion of genes also have important roles.
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Perspective
RNA–Seq: a revolutionary tool for transcriptomics
Zhong Wang, Mark Gerstein & Michael Snyder
The development of high–throughput DNA sequencing methods provides a new method for mapping and quantifying transcriptomes — RNA sequencing (RNA–Seq). This article explains how RNA–Seq works, the challenges it faces and how it is changing our view of eukaryotic transcriptomes.
CURRENT ISSUE
Research Highlights
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Statistical genetics:
Fitting phenotypes
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Human genomics:
Towards an individual view
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RNA World:
Antisense transcripts get involved
WIKI
Nature Reviews Genetics WIKI
Nature Reviews Genetics presents a first for Nature Publishing Group — a Review that can be commented on, updated, and added to by readers using WIKI features. The Review explores the past, present and future of the biology cyberinfrastructure.
More Genetics
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Recommended Links
Links recommended by the Editors
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Web Focus Collection
Selected articles from the Nature Publishing Group on key current topics
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Article Series
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Genetics Conferences
A calendar of forthcoming meetings and workshops from across the field of genetics and genomics.
Noticeboard
Supplement on genomic medicine in developing countries
This collection of Perspective articles describes human genome variation studies taking place in Mexico, India, Thailand, and South Africa. It discusses the challenges and opportunities facing these and other developing countries in harnessing genomics for the benefit of their populations.
Milestones in DNA technologies
Nature Methods, Nature Reviews Genetics and Nature are proud to present The Nature Milestones in DNA technologies, a series of articles and commentaries highlighting the most influential developments in DNA–related techniques over the past half–century.
Visit the Milestones website made freely accessible thanks to the support of QIAGEN.
Focus on Global challenges
This web focus accompanies a special issue of Nature Reviews Genetics that explores a range of areas in which genetics can be put to use in tackling these issues. Topics include: crop genetic manipulation to improve yields and provide resistance to environmental stress; approaches in plant genetics to allow economical biofuel production; and the genetic monitoring of effects of environmental change on the world's biodiversity.
Web focuses
A Web Focus is a selection of articles on a related theme drawn from the entire Nature Publishing Group family of journals. With content ranging from Research Highlights, Reviews and Perspectives through to primary research papers, a Web Focus provides a panoramic view of a key area of biology.
RNAi animation
Nature Reviews Genetics and Arkitek present an animation of the RNAi process. Click here for access to the accompanying RNAi Web Focus, which includes relevant content from across Nature Publishing Group.
Statistical genetics audio supplement
How will advances in statistics aid genetic analyses? Find out what the experts think in our Focus audio supplement: 'Genetics by numbers'
Nature Omics gateway
The Nature Omics gateway is a comprehensive compilation of large-scale genomic biology content, drawn from the complete range of Nature Publishing Group publications. Content includes research and review articles, news, commentaries and research highlights.
Journal Citation Reports, Thomson, 2007