British Journal of Pharmacology

Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain

R Clinckers — October 6, 2008

Impact of efflux transporters and of seizures on the pharmacokinetics of oxcarbazepine metabolite in the rat brain

British Journal of Pharmacology advance online publication, October 6, 2008. doi:10.1038/bjp.2008.366

Authors: R Clinckers, I Smolders, Y Michotte, G Ebinger, M Danhof, R A Voskuyl & O Della Pasqua

Retraction: Sex differences in the expression of sodium/calcium exchanger influence the arrhythmia phenotype in the long QT syndrome type 2

G Salama — May 19, 2008

Retraction: Sex differences in the expression of sodium/calcium exchanger influence the arrhythmia phenotype in the long QT syndrome type 2

British Journal of Pharmacology advance online publication, May 19, 2008. doi:10.1038/bjp.2008.183

Authors: G Salama, B London, L J Kerchner, N R Salama & T Liu

5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles

F Afzal — September 1, 2008

5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.339

Authors: F Afzal, K W Andressen, H K Mørk, J M Aronsen, I Sjaastad, C P Dahl, T Skomedal, F O Levy, J-B Osnes & E Qvigstad

CGRP blockers in migraine therapy: where do they act?

L Edvinsson — September 8, 2008

CGRP blockers in migraine therapy: where do they act?

British Journal of Pharmacology advance online publication, September 8, 2008. doi:10.1038/bjp.2008.346

Author: L Edvinsson

Importance of serum high-density lipoprotein levels to aortic valvular disease

O C Yontar — September 1, 2008

Importance of serum high-density lipoprotein levels to aortic valvular disease

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.348

Authors: O C Yontar & M B Yilmaz

Diastereoselectivity of the P2Y11 nucleotide receptor: mutational analysis

D Ecke — September 29, 2008

Diastereoselectivity of the P2Y11 nucleotide receptor: mutational analysis

British Journal of Pharmacology advance online publication, September 29, 2008. doi:10.1038/bjp.2008.352

Authors: D Ecke, B Fischer & G Reiser

Peroxynitrite: in vivo cardioprotectant or arrhythmogen?

P Eaton — September 22, 2008

Peroxynitrite: in vivo cardioprotectant or arrhythmogen?

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.372

Authors: P Eaton & H Clements-Jewery

Post-injury baicalein improves histological and functional outcomes and reduces inflammatory cytokines after experimental traumatic brain injury

S-F Chen — September 8, 2008

Post-injury baicalein improves histological and functional outcomes and reduces inflammatory cytokines after experimental traumatic brain injury

British Journal of Pharmacology advance online publication, September 8, 2008. doi:10.1038/bjp.2008.345

Authors: S-F Chen, C-W Hsu, W-H Huang & J-Y Wang

CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat

J Zeller — September 8, 2008

CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat

British Journal of Pharmacology advance online publication, September 8, 2008. doi:10.1038/bjp.2008.334

Authors: J Zeller, K T Poulsen, J E Sutton, Y N Abdiche, S Collier, R Chopra, C A Garcia, J Pons, A Rosenthal & D L Shelton

Slow delayed rectifier K+ current block by HMR 1556 increases dispersion of repolarization and promotes Torsades de Pointes in rabbit ventricles

P P-S So — October 6, 2008

Slow delayed rectifier K+ current block by HMR 1556 increases dispersion of repolarization and promotes Torsades de Pointes in rabbit ventricles

British Journal of Pharmacology advance online publication, October 6, 2008. doi:10.1038/bjp.2008.354

Authors: P P-S So, P H Backx & P Dorian

Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK

T Kobayashi — August 18, 2008

Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK

British Journal of Pharmacology advance online publication, August 18, 2008. doi:10.1038/bjp.2008.327

Authors: T Kobayashi, T Nogami, K Taguchi, T Matsumoto & K Kamata

Hot target on nociceptors: perspectives, caveats and unique features

J Szolcsányi — November 10, 2008

Hot target on nociceptors: perspectives, caveats and unique features

British Journal of Pharmacology advance online publication, November 10, 2008. doi:10.1038/bjp.2008.374

Author: J Szolcsányi

Pleiotropic action(s) of the bradycardic agent ivabradine: cardiovascular protection beyond heart rate reduction

G Heusch — September 1, 2008

Pleiotropic action(s) of the bradycardic agent ivabradine: cardiovascular protection beyond heart rate reduction

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.347

Author: G Heusch

Intra- and extrarenal arteries exhibit different profiles of contractile responses in high glucose conditions

K Nobe — September 22, 2008

Intra- and extrarenal arteries exhibit different profiles of contractile responses in high glucose conditions

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.365

Authors: K Nobe, Y Nezu, N Tsumita, T Hashimoto & K Honda

trans-Resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulation

Y Tan — September 8, 2008

trans-Resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulation

British Journal of Pharmacology advance online publication, September 8, 2008. doi:10.1038/bjp.2008.330

Authors: Y Tan & L H K Lim

Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by α2A-adrenoceptors: a mechanism of action distinct from morphine

A Nazarian — September 1, 2008

Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by α2A-adrenoceptors: a mechanism of action distinct from morphine

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.341

Authors: A Nazarian, C A Christianson, X-Y Hua & T L Yaksh

Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death

L Formentini — September 22, 2008

Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.370

Authors: L Formentini, P Arapistas, M Pittelli, M Jacomelli, V Pitozzi, S Menichetti, A Romani, L Giovannelli, F Moroni & A Chiarugi

The guinea-pig tracheal potential difference as an in vivo model for the study of epithelial sodium channel function in the airways

K J Coote — September 22, 2008

The guinea-pig tracheal potential difference as an in vivo model for the study of epithelial sodium channel function in the airways

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.363

Authors: K J Coote, H Atherton, A Young, R Sugar, R Burrows, N J Smith, J-M Schlaeppi, P J Groot-Kormelink, M Gosling & H Danahay

Effects of excitatory and inhibitory neurotransmission on motor patterns of human sigmoid colon in vitro

M Aulí — September 1, 2008

Effects of excitatory and inhibitory neurotransmission on motor patterns of human sigmoid colon in vitro

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.332

Authors: M Aulí, E Martínez, D Gallego, A Opazo, F Espín, M Martí-Gallostra, M Jiménez & P Clavé

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

A A K El-Sheikh — August 25, 2008

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

British Journal of Pharmacology advance online publication, August 25, 2008. doi:10.1038/bjp.2008.343

Authors: A A K El-Sheikh, J J M W van den Heuvel, J B Koenderink & F G M Russel

Use of atorvastatin as an anti-inflammatory treatment in Crohn's disease

O Grip — September 22, 2008

Use of atorvastatin as an anti-inflammatory treatment in Crohn's disease

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.369

Authors: O Grip, S Janciauskiene & A Bredberg

An endogenous regulator of inflammation, resolvin E1, modulates osteoclast differentiation and bone resorption

B S Herrera — September 22, 2008

An endogenous regulator of inflammation, resolvin E1, modulates osteoclast differentiation and bone resorption

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.367

Authors: B S Herrera, T Ohira, L Gao, K Omori, R Yang, M Zhu, M N Muscara, C N Serhan, T E Van Dyke & R Gyurko

Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells

D Kempuraj — September 22, 2008

Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.356

Authors: D Kempuraj, M Tagen, B P Iliopoulou, A Clemons, M Vasiadi, W Boucher, M House, A Wolfberg & T C Theoharides

Viral vectors: from virology to transgene expression

D Bouard — September 8, 2008

Viral vectors: from virology to transgene expression

British Journal of Pharmacology advance online publication, September 8, 2008. doi:10.1038/bjp.2008.349

Authors: D Bouard, N Alazard-Dany & F-L Cosset

Desensitization of the soluble guanylyl cyclase/cGMP pathway by lipopolysaccharide in rat isolated pulmonary artery but not aorta

M S H El-Awady — September 22, 2008

Desensitization of the soluble guanylyl cyclase/cGMP pathway by lipopolysaccharide in rat isolated pulmonary artery but not aorta

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.358

Authors: M S H El-Awady, S V Smirnov & M L Watson

Protective action of doxycycline against diabetic cardiomyopathy in rats

N Yaras — September 22, 2008

Protective action of doxycycline against diabetic cardiomyopathy in rats

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.373

Authors: N Yaras, M Sariahmetoglu, A Bilginoglu, A Aydemir-Koksoy, A Onay-Besikci, B Turan & R Schulz

Identification of α1L-adrenoceptor in mice and its abolition by α1A-adrenoceptor gene knockout

I Muramatsu — September 22, 2008

Identification of α1L-adrenoceptor in mice and its abolition by α1A-adrenoceptor gene knockout

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.360

Authors: I Muramatsu, S Morishima, F Suzuki, H Yoshiki, A S M Anisuzzaman, T Tanaka, M C Rodrigo, B E Myagmar & P C Simpson

Inhibition of fatty acid amide hydrolase produces PPAR-α-mediated analgesia in a rat model of inflammatory pain

D R Sagar — August 25, 2008

Inhibition of fatty acid amide hydrolase produces PPAR-α-mediated analgesia in a rat model of inflammatory pain

British Journal of Pharmacology advance online publication, August 25, 2008. doi:10.1038/bjp.2008.335

Authors: D R Sagar, D A Kendall & V Chapman

Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake

T L Borella — September 29, 2008

Central muscarinic receptor subtypes involved in pilocarpine-induced salivation, hypertension and water intake

British Journal of Pharmacology advance online publication, September 29, 2008. doi:10.1038/bjp.2008.355

Authors: T L Borella, L A De Luca, D S A Colombari & J V Menani

Activation of the transient receptor potential vanilloid-1 (TRPV1) channel opens the gate for pain relief

G Jancsó — November 10, 2008

Activation of the transient receptor potential vanilloid-1 (TRPV1) channel opens the gate for pain relief

British Journal of Pharmacology advance online publication, November 10, 2008. doi:10.1038/bjp.2008.375

Authors: G Jancsó, M Dux, O Oszlács & P Sántha

Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels

A Kiss — September 1, 2008

Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.344

Authors: A Kiss, L Juhász, I Huliák & Á Végh

Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells

Y Ning — August 25, 2008

Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells

British Journal of Pharmacology advance online publication, August 25, 2008. doi:10.1038/bjp.2008.337

Authors: Y Ning, K O'Neill, H Lan, L Pang, L X Shan, B E Hawes & J A Hedrick

Differential role of tachykinin NK3 receptors on cholinergic excitatory neurotransmission in the mouse stomach and small intestine

J G De Man — September 22, 2008

Differential role of tachykinin NK3 receptors on cholinergic excitatory neurotransmission in the mouse stomach and small intestine

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.357

Authors: J G De Man, B Y De Winter, H U De Schepper, A G Herman & P A Pelckmans

H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G

S Muzaffar — September 1, 2008

H2S-donating sildenafil (ACS6) inhibits superoxide formation and gp91phox expression in arterial endothelial cells: role of protein kinases A and G

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.326

Authors: S Muzaffar, J Y Jeremy, A Sparatore, P Del Soldato, G D Angelini & N Shukla

The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor

P Holzer — September 22, 2008

The pharmacological challenge to tame the transient receptor potential vanilloid-1 (TRPV1) nocisensor

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.351

Author: P Holzer

Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product

H Kozłowska — September 22, 2008

Virodhamine relaxes the human pulmonary artery through the endothelial cannabinoid receptor and indirectly through a COX product

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.371

Authors: H Kozłowska, M Baranowska, E Schlicker, M Kozłowski, J Laudañski & B Malinowska

MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models

M Naguib — September 1, 2008

MDA7: a novel selective agonist for CB2 receptors that prevents allodynia in rat neuropathic pain models

British Journal of Pharmacology advance online publication, September 1, 2008. doi:10.1038/bjp.2008.340

Authors: M Naguib, P Diaz, J J Xu, F Astruc-Diaz, S Craig, P Vivas-Mejia & D L Brown

Low doses of α2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance

B Milne — September 22, 2008

Low doses of α2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance

British Journal of Pharmacology advance online publication, September 22, 2008. doi:10.1038/bjp.2008.353

Authors: B Milne, M Sutak, C M Cahill & K Jhamandas